Plasma osteopontin
نویسندگان
چکیده
منابع مشابه
plasma osteopontin level in chronic liver disease and hepatocellular carcinoma
conclusions plasma opn is comparable to afp as a diagnostic marker and is related to the severity of liver involvement in hcc patients. plasma opn is of diagnostic potential value in nafld. background osteopontin (opn) is a secreted glycoprotein and is frequently associated with various tumors. objectives we sought to investigate the clinical usefulness of the level of plasma opn, compared to α...
متن کاملPlasma osteopontin, hypoxia, and response to radiotherapy in nasopharyngeal cancer.
PURPOSE Recent studies have suggested that osteopontin is induced by hypoxia in head and neck cancer cell lines and its plasma level may serve as a surrogate marker for tumor hypoxia and treatment outcome in head and neck cancer. We investigated the response of osteopontin to in vitro hypoxia in nasopharyngeal carcinoma cell lines, and determined plasma osteopontin levels in nasopharyngeal carc...
متن کاملPlasma osteopontin concentrations in patients with cutaneous melanoma
An effective circulating tumour marker is needed for melanoma especially with the advent of targeted therapies. Gene expression studies examining primary melanomas have shown that increased expression of osteopontin (SPP1) is associated with poor prognosis. Studies subsequently reported higher blood levels in melanoma patients with metastatic disease than those without. This study was designed ...
متن کاملHigh plasma osteopontin levels in patients with inflammatory bowel disease.
BACKGROUND Osteopontin (OPN) plays a key role in the progression of T(H)1-immune-mediated disease in models of multiple sclerosis and rheumatoid arthritis. AIM To determine whether plasma OPN levels in patients with inflammatory bowel disease are associated with disease activity. METHODS Plasma samples were obtained from patients with ulcerative colitis (UC, n=30), Crohn's disease (CD, n=30...
متن کاملPlasma Osteopontin Level in Chronic Liver Disease and Hepatocellular Carcinoma
BACKGROUND Osteopontin (OPN) is a secreted glycoprotein and is frequently associated with various tumors. OBJECTIVES We sought to investigate the clinical usefulness of the level of plasma OPN, compared to α-fetoprotein (AFP), as a biomarker for hepatocellular carcinoma (HCC) and to evaluate its diagnostic value in nonalcoholic fatty liver disease (NAFLD) and its relationship with clinical an...
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ژورنال
عنوان ژورنال: Cancer
سال: 2002
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.10709